Last night (Friday June 25) I took an overnight bus from Buenos Aires to Mendoza. Andesmar services much of South America and offer First Class (lie-flat seats) roundtrip (BA to Mendoza) for $144 USD. Tickets are easy to get online and you just need to show up to the station about 30 minutes prior to departure. No need to worry about security, liquids, bag allowances, etc. A word of caution however on bus companies. Andesmar claims to be the "high end" bus service in South America. While the bus was on time and they drove cautiously, the quality of food and bathroom were little to be desired. I hate to see what some of the other discount bus companies offer. Ewe.
Winter in Mendoza (wine country) is not the most favorable time to be here. It is quiet and not packed with tourists. Today the weather was a bit chillier than BA but it's well suited for a nice glass of Trapiche Malbec in a cafe.
Salud!